Genomatica’s robust collection of integrated technologies are key to establishing the company as the true pioneer in the field of chemical bio-manufacturing. These In Silico and Wet Lab technologies include:

In Silico Lab: SimPhenyTM: Proprietary award-winning metabolic modeling and simulation system. Metabolic Model Development: The industry’s pre-eminent collection of predictive metabolic models and     automated systems that facilitate rapid model development. Pathway Predictor: High throughput system for determining all possible biological and chemical transformation     routes to a desired chemical product. OptKnock Strain Design: Powerful proprietary algorithms to couple organism growth to production of desired     chemical products for stable, efficient and high yield bioprocesses. “Omics” and Fermentation Data Analysis and Interpretation: Analysis of complex omics data, including     genomics, transcriptomics, metabolomics, proteomics, and fluxomics, in the context of a model. Bioprocess Modeling and Design: Advanced process and recovery designs that are consistent with organism     and feedstock properties in order to dramatically reduce development timelines.

Wet Lab: Enhanced Evolutionary Engineering: Proprietary methods for adaptive evolution of microbes to achieve optimal     performance under process conditions High-Throughput Experimentation: High throughput cloning, screening, and fermentation 13C Flux Analysis: Isotopic labeling experiments and the most accurate computation of internal flux     distributions for large scale metabolic networks to determine network and pathway bottlenecks